June 7, 2008 - 4:49pm
I heard that methadone is way better and cleaner than methadose. Anyone know if they use the exxact same recipe or are they different formulas.
June 7, 2008 - 6:51pm
#2
methadose
when i drank the pink liquid, for some reason i got sick, like allergic sick, but the methadose 40's thatdissolve in water worked great....
June 9, 2008 - 9:38am
#3
methadose is weaker
When I attended a meth clinic a few years back at first they were giving Roxane(at first wafers and then liquid). Then after a while they started diving methadose. It was much less potent. I thought that it was in my head. Then one day at the clinic I noticed that there was a flyer posted beside the dosing window stating that because of the many complaints about the methadose that the clinic would be switching to VistaPharm methadone. IMO it is as good as the Roxane.
June 11, 2008 - 9:12am
#4
Done Vs DOSE Vs other brands.
Please all DONEDOSERS please give me your two cents about this bc they said i coulc have a choice. THe actual Done doctor told me that somm ppl think its weaker but i dunno.... What are those orange 40 mg wafers those just look cool
June 11, 2008 - 9:34am
#5
Dolphine
i believe there called Dolphine they r 40mg just like the methadose 40s. They get dropped in water n stirred they really arent that bad i have taken b4
June 11, 2008 - 11:48am
#6
The orange wafers are made
The orange wafers are made by Roxane and are methadone dispersable tablets. If you have ever gotten a script for these they say M'crodt specific, which leads me to believe they get the ingredients from mallincrod't and have the exact same medicine in them. The only difference I have found b/w the two wafers is that the Roxane brand are more crumbly and dissolve easier.
Check with a licensed MD before you take any suggestions!
June 11, 2008 - 2:08pm
#7
Methadone, Methadose, Dolophine
I have read in many reliable sources that all of the dolophine hcl in all forms tablets, wafers, pills and liquid forms of methadone all are supplied bye Mallnk/Tyco Pharmacuuticals. So Roxane purchases their dolophine from Mallnk and then processes it into pills, liquid and so on. I know that their are many many complaints about mallnk products but all the methadone comes from them. I know personally that I think that the roxane 5mg and 10mg tablets and the mallnk 5mg and 10mg tablets (the rectangle ones not methadose) are very similar. I have also had the roxane liquid and I did not like it at all. I have always prefered the pill form. The liquid just doesnt work correctly for me. It comes across strange to me that the roxane methadone is "better" than mallnk Methadose and mallnk generic methadone...the rectangle ones. When it all comes from one source. It must have to do with the processing bye the individual pharmaceutical company. Does anyone know if Lilly still manufactures the 40mg wafer?
June 11, 2008 - 3:17pm
#8
I just think it is a
I just think it is a common misconception that Mallinckrodt supplies all the Methadone. I think this came about because if you go to Mallinckrodts website, you can see a list of available bulk compounding powders and listed is Methadone HCL. They also list hydrocodone,codeine,morphine etc. it doesnt mean they supply everyone with these drugs.
A lot of people also think that Mallinckrodt was the first manufacturer of methadone in the US. Roxane was approved to manufacture Dolophine tablets in August 1947, and Mallinckrodt was approved to manufacture there bulk powder for custom compounding in December 1947, but wasnt approved for Methadose tablets until April 1993 and generic Methadone tablets until April 2004.
June 11, 2008 - 3:42pm
#9
Thank You
Thank You Solo5010 you are very knowledgable. You are a asset to this site..
anthony
June 15, 2008 - 6:12pm
#10
Well now im confuse...All i
Well now im confuse...All i know is methadose. Ive never taken anything different. My dose right now is 140. I really want to try a diff brand. is there anyway i could go about that?
June 15, 2008 - 8:46pm
#11
Done Doser
Donedoser, are you on the clinic or are you prescribed methadone from a MD. If you are RX you can have the DR write the script as Dispense as Written. Or you can go or call pharmacies and ask them what brand of methadone they dispense and then ask them if they could order Roxane brand or the Mallnk brand of methadone.. any more questions just ask
June 15, 2008 - 9:09pm
#12
Mallinckrodt is a bulk
Mallinckrodt is a bulk chemical production company so it's nothing for them to produce huge amounts of bulk and supply it to whoever wants it. Most pharmaceutical companies buy bulk from others and formulate their products. But, like solo noted, there are others in the bulk biz from all over, including companies in: USA, Europe, India, Japan, China, mid-east, Korea and other Asian countries, South America, and et cetera. I guess the only place left out is Antartica.
June 16, 2008 - 12:58am
#13
Stuck btwn a rock and a hard place
I go to a done clinic and i had an allergic reaction to the dye and broke out in hives and puffed up. I went to the ER and They agreed that it was from the concentration of the red dye in the methadose liquid or methadone.I continued to go to the clinic bc they agreed to put me on wafers. At first they switched me to dose wafers and everything cleared up and we thought we soved the problem. Now they have been %?%!*#&& about how much time and energy is wasted on dispensing wafers and having to break them in half and having to count them every week or day or some BS.They now immunized me to 10 to -20-30-60 mgs of liquid and 2 wafers. Ive noticed rashes and symptoms of allergic reactions. They seem to discriminate against me bc i complain about the red dye and they think I just want the pills. Which i think is terrible treatment. Ive gotten perscribed clonozepam for my benzo addiction and its only gotten stonger...so Ive checked out the other clinics and one is a government owed one that takes months to get inbto and one has a crooked doc who got busated for writing scripts of hardcore opiates to his Clinc patients. I was going to tranfer there bc they said theyd give me wafers.....should i still go to that one....man i dont know. Im lost.
June 16, 2008 - 3:42am
#14
where is your paperwork from
where is your paperwork from the ER saying you are allergic to the red dye? didn't you say they told you to present the paperwork from a doc saying this and that they would quit giving it to you?
I'm a social worker, not a medical professional. All comments and thoughts are simply my opinion and experience.
June 19, 2008 - 3:03pm
#15
Flounder, you are very
Flounder, you are very mistaken. The rules set down by the United Nations, FDA and Dea do not allow Schedule 2 Narcotics to be imported into the United States. There are currently only 3 companies who are allowed to manufacture Bulk Methadone, Mallinckrodt is one of them. There is no "legal" Methadone coming from China,South Korea etc.
June 19, 2008 - 6:45pm
#16
Although you are correct
Although you are correct that M'crodt supplies a lot of bulk pharmacuetical ingredients this isn't why I feel they supply Roxane. Personally I don't know and don't really care but if you look on Mcrodts website you will see a pill that is a 40mg orange wafer exactly the same as Roxanes. And since M'crodt doesn't sell an orange tablet is must be going somewhere. And you are correct that Roxane came out with "Dolophine" but mallincrodt was the first to produce Methadose. Both being the same drug methadone hcl. Like I said, on the Roxane script bottle it says "M'crodt specific" which leads me to believe(regardless who the chemicals come from) that they are they exact same formulation regardless of how they look or who the manufacturer is. What really amazes me is that at the doses people on this board are taking even a 20% difference would be barely noticable if at all, IMO.
Check with a licensed MD before you take any suggestions!
June 19, 2008 - 9:28pm
#17
Racemic?
One major consideration is whether you are getting racemic Methadone or a specific enantiomer (either the levorotary enantiomer or the dextrorotary enantiomer). The levorotary form (levomethadone) is more potent than the dextrorotary form, and causes fewer side effects like QT/QTc prolongation (a potentially serious cardiac effect that can lead to torsade de pointes). In the U.S. generally methadone is available almost exclusively as a racemic compound including both forms in roughly equal amounts per dose, but levomethadone is available and produced internationally. Because it is CII and levomethadone is primarily found in europe, I am not sure of the specific availability of levomethadone in the U.S. (I have never dispensed nor prescribed levomethadone myself).
Just food for thought...
/Xtrasystole - BS.Bio, MS Anesthesiology, Pharm/M.D.
Always check with a physician/pharmacist licensed where you live before taking medication. My license does not extend past the state of my practice.
June 20, 2008 - 12:34am
#18
THANKS
THANKS Y'ALL
All generics can be plus or minus 20% off the original branded formula. I have had the Roxane and mallinkrodt 10mg tabs and never noticed a difference.