July 30, 2006 - 3:00am
#2
As far as I understand
As far as I understand it, Hydrocodone and Oxycodone are both semi-synthetic opiod agonists. Oxycodone is derived from Thebain, NOT Morphine. Hydrocodone can be derived from both thebain or codeine. They are both narcotic analgesics and controlled substances.
Derivatives of Morphine include Hydromorphone and Oxymorphone.
Tramadol is a synthetic atypical opiod. It is not considered narcotic at this time, but there is always an ongoing debate whether it is or is not and whether it should be or not (on this site, and in the medical profession/community). It is not a controlled substance. Tramadol was originally said to have a low risk of dependency, however the prescribing info for Ultram/Tramadol carries the warning that it may be habit forming.
From www.wikipedia.com
Opiate:
"The term is often incorrectly used to refer to all drugs with opium- or morphine-like pharmacological action, which are more properly classified under the broader term opiod.
The main opiates drived from opium are morphine, codeine and thebaine"
Also from www.wikipedia.com
Opioid:
"Although the term opiate is often used as a synonym for opioid, it is more properly limited to the natural opium alkaloids and the semi-synthetics derived from them"
July 30, 2006 - 4:16am
#3
Hmmm....
"Oxycodone is derived from Thebain, NOT Morphine."
Opioids can be classified as the following:
Partially synthetic derivatives of morphine - Heroin, oxycodone, oxymorphone,
Naturally occurring opium derivatives - Morphine
Synthetic compounds - Fentanyl, alfentanil, levorphanol, meperidine, methadone, codeine, propoxyphene
http://www.emedicine.com/med/topic1673.htm
My comments are my opinions based on the questions posted on this message board and should be taken purely as is and not as medical gospal. Please consult medical concerns with medical proffesionals. Thank You!
July 30, 2006 - 5:46am
#4
I see links out there saying
I see links out there saying it comes from morphine, but then I find contradictory information. I did in depth research and used some other very credible sources that I can't link to because they are subscription and I still am leaning towards thebain.
Oh well, im not here to argue, just wanted to post the specific links from which I based my previous post.
"Oxycodone is a very powerful and addictive opioid analgesic medication synthesized from thebain."
http://en.wikipedia.org/wiki/Oxycodone
Here is the monograph from GSM (Gold Standard), a source we can all agree is very credible:
"Oxycodone is an oral semisynthetic opiate agonist derived from the opioid alkaloid, thebaine, and is similar to other phenanthrene derivatives, such as hydrocodone and morphine."
July 30, 2006 - 4:53pm
#5
Partially synthetic
I'm definitely not saying that you are wrong I'm just making a point that we could both be correct in certain aspects, but i researched and found that oxycodone is derived semi synthetically from morphine, but in all reality morphine and oxycodone etc... are all one in the same meaning that they are all closely related and could not be without the other.
You are right incognito in your answer that oxycodone is derived straight from thebaine, but oxycodone can be derived semi synthecially from morphine. In all instances I thank you for raising this debate and would welcome more info and corrections on this subject.
My comments are my opinions based on the questions posted on this message board and should be taken purely as is and not as medical gospal. Please consult medical concerns with medical proffesionals. Thank You!
August 3, 2006 - 11:55pm
#6
Tramadol
Hi 717,
Not sure what you want to know here exactly but here are some experiential views of Tramadol.
- Taken in larger than prescribed doses, it lowers your seizure threshold. Keeping that in mind, I have stupidly far exceeded those doses and been lucky.
- Their is nothing like an opiate buzz from taking them in normal or higher quantities. Absolutely nothing.
- Their time to onset in action is longer than opiates like codeine, hydrocodone, morphine, dilaudid, taking about 60-90 minutes.
- I would say their effectiveness in relieving pain is no more than 800 mg Ibuprofen.
- The pain-killing effects or side effects last much longer than opiates. Perhaps 8-10 hours.
- With exceeded doses, I have noticed urethral sphincter muscle effects and dribbling, clouding of hearing, nausea and vomiting.
- There has been discussion on the alt.drugs.hard board that they may help relieve some opiate withdrawal effects and I have found them slightly helpful against hot/cold sweating, anxiety symptoms of w.d.
- I don't know about being habit-forming (can't imagine ANYONE wanting to abuse them on a regular basis), but a tolerance to dosage is definite.
I hope this is some helpful.
Take Care, Stay Safe, God Bless,
Karen M.
November 19, 2006 - 11:13am
#7
Tramadol
Tramadol is very addicting. In recent years the DEA has reported increasing trends of Tramadol abuse particularly in people that have a past history of substance abuse. I personally take Tramadol and became addicted to them myself. In my opion as far as the difference in Tramadol and Hydrocodone is this: When taken in larger doses than prescribed, Tramadol can create a euphoric state that is equal to and often exceeding that of Hydrocodone and other narcotics. This effect lasts about 8 house as opposed to say hydrocodone that for me, lasts only about one hour. I personally prefer Tramadol over any other narcotic because of the long lasting effects when taking 250mg or more. Also once Tramadol is in your system on a regular basis and exceeding the normal prescribing dosage, the euphoric effects tend to be almost equal to that of Oxycontin. This is just my personal experience with Tramadol however, some people have reported not "feeling" anything at all from taking Tramadol.
February 2, 2007 - 12:04pm
#8
I have just found out that
I have just found out that my husband is abusing tramadol He got it filled like 5 times in DEC. I caught him he lied and lied and finally told me the truth after he knew that I alreadyknew... BUt he says that it does nothing at all just makes his oxycodo last longer.. I think that he is full of it and I also think that he is abusing his oxycodo.. I don't knwo what to do about this.. We have 3 kids and I can't believe that I am in this.. But he is abusing I am pretty sure.. What to do?
February 2, 2007 - 12:37pm
#9
barbie, I'm sorry you
barbie,
I'm sorry you are in this position. There are numerous threads on this site that deal with tramadol, and addiction. Possibly, too many threads that relate to tramadol. As I'm sure you already know, tramadol is sometimes abused, despite it's unscheduled regulation.
I don't know of any other advice I can give, other than to say that I feel for you.
Here is a website that has been posted concerning opiate abuse and detoxing, take it for what it's worth.
Gtrplayer
February 7, 2007 - 10:39am
#10
My husband claims that there
My husband claims that there are 2 different types of Tramadol one with codine and one with out and the people on here must be taking the one with codine in it he says because the one that he takes will not do this to you.. I personally do not beleive a word that he tells me and I think that there is just one Tramadol and one only.. And yes its the one that he is abusing....
Thanks for all your thoughts...
February 7, 2007 - 10:57am
#11
your husband is WRONG there
your husband is WRONG there is no such thing as tramadol with codiene in it.
there is tramadol with tylenol and tramadol without tylenol but that is about it.
all thoughts and opinions expressed are those of my own and should not be mistaken for medical advice. i am not a doctor nor a pharmacist. all medical questions should be answered by a licensed pharmacist, doctor, or primary care manager.
February 7, 2007 - 12:09pm
#12
I agree with Phisher. The
I agree with Phisher. The only other ingredient to a tramadol preparation, that I know of, is acetaminophen. If the drug is pure tramadol, it's ultram. If it has acetaminophen, it's Ultracet. Either way, neither combinations contain Codeine.
I hate to say this, but with an addict, it's always the "other person" who doesn't know what they are talking about. I feel bad for you, but rest assured, we do know what we are talking about. Ask him to provide you with PROOF that there is a tramadol with codeine in it. Don't be surprised if you get, "Well, I'm not sure of the exact name of it". It doesn't exist.
Gtrplayer
February 8, 2007 - 7:54am
#13
Does anyone have any
Does anyone have any suggestions on how to get someone like this help? He is saying that he does not have a problem and the month of Dec. is the first time that he ever got his Tramadol filled like that,, I don't hardly beleive him I mean he might not have gotten it filled 5 times on the other months but I can remember at least 2 times where he had it filled and claims that they didn't put it in the bad or if they did he must have trashed it( YEA RIGHT) I did beleive him at the time but now I think back on it and look at today he was lying the whole time...Tramadol is one of Walmarts $4.00 drugs.. This makes it easier to get... He is still saying that he is not abussing his medicines and everyone knows that he is... This week his mood had been ALOT better so we are getting along good... But just don't know what to do...
I would take any suggestions that I can get..
Thanks cindy
February 9, 2007 - 6:29pm
#14
Sorry to bring this thread
Sorry to bring this thread back up, but I have a question for barbiedoll1973_tn
You said that he went through 5 refills in one month? Out of curiosity, how many pills are rx'd at a time and what are the dosing instructions? Usually, a pharmacy will not fill a prescription that many times in one month.
Gtrplayer
April 12, 2007 - 1:20pm
#15
i dunnoooooo
I used to be heavily addicted to opiates (oxycontin in the earlier stages) and I can tell you that one time I came across tramadol and it did absolutely nothing. It gives like a little bit of a euphoric affect. I couldn't see why anyone would want to abuse it, but it is longer lasting so his explanation that it makes his oxy last longer does make sense. I duno, maybe you should relax and be a little more trusting, or if you really think it's bad and want to help don't approach him like you're his mother. Act like a wife that loves him and is concerned for his well-being, not wether or not he's lieing to you.
April 12, 2007 - 1:27pm
#16
the weirdest part is that
the weirdest part is that you're more concerned about the tramadol than the oxy. The potential for abuse and addiction in oxycodone/contin is way higher than that of tramadol. He could have started getting withdrawals from the oxy and been using the tramadol to try to switch over and get off the oxy, which if he was in a bad mood and didn't look well could have likely been what he was doing because he would probably still get a little withdrawal trying to switch. I duno, but oxy is something i would be alot more concerned about than tramadol.
November 20, 2008 - 12:16am
#17
Agree with facedown
Act like a wife not a mother. GET HIM INTO REHAB...just speaking from experience. Especially since you have kids.
Keep in mind I am not a; doctor, a pharmacist, a counselor, or any professional for that matter. My posts are not meant for medical advice, nor should you use it that way. I am simply a college student/ guinnea pig/ drug addict. Thanks for your concern.
Tramadol is an Non-opiate Synthetic Analgesic