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Interesting document on Effexor discontinuation syndrome, and a good website to boot

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This is information I found on a website called www.crazymeds.us 

They have all of the psychiatric drugs listed, although a few only have limited information, but alot of good and humourous information about drugs millions of americans take without thinking twice. This article is taken directly from the website. Sorry I couldn't edit it better, it kept deleting pages for some reason instead of lines???

US Brand Name:

 

Generic Name:

Other Forms:

What is Effexor XR:

Effexor XR is an

 

What are Effexor's FDA Approved Uses: Effexor XR is approved to treat:

Major Depressive Disorder - Effexor XR approved October 1997, immediate-release approved December 1993

General Anxiety Disorder - Effexor XR approved 11 March 1999

Social Anxiety Disorder - Effexor XR approved 11 February 2003

Panic Disorder - Effexor XR approved 18 November 2005

What are Effexor's Off-Label Uses:

Bipolar Depression (dodgy for bipolar 2, not a good idea for bipolar 1)

Fibromyalgia

Arthritis

Chronic Fatigue

Multiple Sclerosis

Lupus

Headaches

Irritable Bowel Syndrome (IBS)

ADD/ADHD

Eating Disorders

in addition to approved uses, Effexor XR (venlafaxine hydrochloride) is also prescribed for:

 

Effexor XR

A link here will take you to the official website for the drug.

A link here will take you to the official website for the drug.antidepressant, specifically a multiple reuptake inhibitor

 

 

 

 

 

Effexor's Pros:

There are two last resorts among the modern meds to cure the deepest, blackest depression when your doctor is just switching you from one horsie to another on the med-go-round: Effexor XR (venlafaxine hydrochloride) and Remeron (mirtazapine). Either in combination with an antipsychotic

would really get you out of that hole of despair, but first you should throw away every mirror and scale in your house and buy expandable clothing. But for deep, despairing clinical depression that needs to respond to the standard tweaking of the three most popular neurotransmitters, Effexor XR (venlafaxine hydrochloride) often pulls people out of the abyss.

 

The usual for SSRIs and NRIs

- headache, nausea, dry mouth, sweating, sleepiness or insomnia, and diarrhea or constipation, weight gain, loss of libido and a host of other sexual dysfunctions. Most everything but the weight gain and sexual dysfunctions usually goes away within a couple of weeks. Although some women will notice that the sexual side effects will diminish above 200-225mg a day when the norepinephrine kicks in. Maybe.

 

side effects page.

Effexor's Not So Common Side Effects: Increased or lowered blood pressure, sweating, ^%#^$&*@, anorexia, twitching, shock-like sensations.
Also alcohol intolerance and/or alcohol abuse. So Effexor XR (venlafaxine hydrochloride) is going to be just the thing to talk about at AA meetings.
I used to have these last two listed as rare side effects, but I've received way too many e-mails and have read far too many similar reports on various other sites after putting up this page about both of them. As is often the case here, the anecdotal evidence will often trump what is in the

 

US PI Sheet. Best guess to date as to why both of these side effects can happen - Paul of Leeds (in the U.K.) posits that Effexor's broad spectrum use of liver enzymes probably interferes with alcohol clearance and tolerance, thus leading to the type of alcoholism that affects people without the proper enzymes to effectively metabolize alcohol. Between that and the way Effexor XR works your liver, you're probably better off giving up booze entirely if you're taking this med.
These may or may not happen to you don't, so don't be surprised one way or the other. Although I make no promises about the alcohol abuse

Effexor's Freaky Rare Side Effects:

Someone's reflexes increased and someone else's breasts got bigger, proving that there is no pleasing some people. Someone else's hair changed color and, really, no Revlon was involved. But the most disturbing freaky rare side effect with Effexor XR (venlafaxine hydrochloride) is what Wyeth disingenuously calls "withdrawal syndrome," that once you acclimate to Effexor (venlafaxine hydrochloride) you are basically hooked for life. If not on Effexor XR then at least on some

 

SSRI to take the worst of the edge off. The discontinuation syndrome never goes away if you try to stop. For someone with unipolar depression that's a pain in the @!^, but something you might be able to work around barring any really adverse side effects, but for someone who is bipolar you can be royally screwed because Effexor XR (venlafaxine hydrochloride) can really aggravate mania and especially rapid cycling.
You aren't going to get these. I promise.

.

 

Interesting Stuff Your Doctor Probably Won't Tell You:

 

When you're fully saturated with the medication and less prone to peaks and valleys of effects. You still might have peaks of effect after taking many meds, but with a lot of the meds you'll have fewer valleys after this point. In theory anyway.

How Long Effexor Takes to Work:

Up to one month.

 

SSRI discontinuation syndrome., let alone get them to admit that Effexor's symptoms are the absolute worst and the longest lasting of all serotonergic drugs. The discontinuation from Paxil (paroxetine

) is bad enough, it's much, much worse with Effexor (venlafaxine hydrochloride).

 

 

 

 

 

 

 

 

 

 

Comments:

 

 

 

 

multiple reuptake inhibitor, acting sort of as both an SSRI and NRI

, so be sure to read up on all three classes of meds, as those pages will cover a lot of stuff common to all meds similar to Effexor (venlafaxine hydrochloride).

SSRIs

Effexor (venlafaxine hydrochloride) is likely to trigger not just mania, but rapid cycling. Combine that with the very rare, but still real chance that you could be stuck taking Effexor (venlafaxine hydrochloride) for the rest of your life, even if it doesn't work. That complicates things greatly in Bipolarland.

SSRIs

, forget about Effexor (venlafaxine hydrochloride) entirely.

 

 

 

 

 

 

 

our Effexor Board.

Manufacturers:

 

Wyeth

Sample US Cost of Effexor: $100 for 30 75mg XR capsules.

As of 11/10/2003. Full retail for the uninsured. Go ahead and gloat, citizens of civilized countries and all of you with full medical coverage.