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I have experienced this also. When I read it in the post I thought wow could my pill usage be causing the hiccups? It only seems to happen late in the evening and I never put the two together. Hiccups are a sign of APAP OD / poisioning? If so I am worse off than I thought. This is an alarming revelation for me. It does not happen everyday. But looking back I do see a correlation between the amount of pills I use and the occurence of hiccups. I am rambling.....this forum is awesome. I am always learning from it.

I am using up to 7g some days. I try to stay under 4g but I am not always able to. Today I will hit close to 5.55g and have not experienced any hiccups.

>> When your body starts slowing down and toxins don't get pushed through your bloodstream as quick because your heart and all organs (even thought the brain can remain highly active) the tylenol flow 'slows' down and remains in the system a lil longer, not that it doesn't break down at the same rate, because the rule with half-lives is that it dictates that the chemicals rate at which they breakdown always remains at a constant rate, however, it doesn't exit your body through your excretory system as quickly.(i like that name for it ) your heart beats slower, thus blood pressure and speed of flow is reduced as well in all other "tubes" in your body. That is why mostly at night  and near or during bed/sleep hours the hiccups come the most. Tylenol is not different from water, food, pills, anything...EVERYTHING IN MODERATION. Be mindful of the amounts, i can't stress it enough.

Remember, this is very important, In ONE 24 hour period, the MAXIMUM amount of acetominophen one can ingest is 4000mg, up until this point APAP is toxic at all to you and you can clean it out of your sytem like a breeze, however even keeping high levels of tylenol everyday is a strain on your liver. Once you pass that maximum amount tylenol/acetomenophen/APAP becomes VERY toxic, and is one of the more deadlier chemicals to your liver and its functionality, obviously the more past that point the harsher it is. If this has been a constant dose and are past that point more than a few times, hell even one time could ruin your liver. I heard a story of one guy who takes way more, everyday, and his liver is fine, i know people who went past it once and permanently hurt his liver. Everyone is different, but if you really have gone past a lot, then you should go get your liver checked. you should already be doing this if you are Rx'd high doses of hydrocodone/apap to make sure the tylenol isn't adversely affecting your body over time. That is why cancel the whole equation by taking oxycodone with no tylenol. started with 5mg's, then at 15mg, i believe next week my doctor will have me bump it for the last time to the 30mgs. I never have to worry about tylenol again.

I am not a doctor, i am an experienced individual

Enigmuh

>>the oxycodone doesn't help either i'm just saying i've had that side effect, and so have many other reported cases of too much tylenol, it may not be the only cause of hiccups, i know its not good for you to be taking over the amount regardless. the point is valid, i'll check and make sure,ifim wrong than i'm wrong but don't take more than 4000mg is my main point

I am not a doctor, i am an experienced individual

Enigmuh

>>neither waas i my friend, it is hard to discern intentions when clarifying one's self, i never take anything personally, i take it more as i am learning. I find it hard to explain things because my tendencies is to use the clearest/best words to describe what i say, not necessarily what words are most commonly used among "regular" people. i am a perfectionist as well as a word nerd, so i tend to have a more scientific vernacular (like with that word) when i explain chemistry, pharmacology, and sometimes psychology, but psych i usually use common terms and words. i'm not trying to sound smart, as my brothers would put it, but rather use words with correct definitons, not slang, homie. haha. bballin, you are correct, and maybe i am partially wrong, but as long as somehow the correct info comes out, i'm cool with that

I am not a doctor, i am an experienced individual

Enigmuh

>> i know that some opiates have the side effect of drying the mount, my nose has been considerably dry since i started a consistent regiment,i think with that in mind there might be a strong possibility there is a side effect in a small population with that. But my opinion is that it is allergy season and if you have not had any prior symptoms, perhaps ther is something you are allergic to and are unaware of it.

How long has the runny nose been going on, just recently, or since you started your opiate regiment? Have you recently changed meds at all? do OTC congestants work? and last question, besides opiates, are you taking anything else? this is very interesting to me and i'd like to know the answer, let me know your responses and we'll go from there

I am not a doctor, i am an experienced individual

Enigmuh

7g of APAP....please don't do that.....your liver loves you, and i know deep down inside you love it too. Seriously, keep it at 4g and under..and yeah solo excessive lacrimation is a classic w/d sign...i always felt like i had the flu. Ive never noticed having hiccups when i'm taking straight APAP, but have noticed them when i take lortab or whatever...AND Xanax has on multiple occasions caused me to have hiccups, just the xanax alone, I know this because several times when it's happened to me, I wasn't taking any hydrocodone/APAP....It sucks cuz they don't go away that easy....If you get them that bad...thorazine works for treating "Chronic" hiccups...Ray 

Remember: Just do it.. EVERY PILL  EVERY DAY