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LETHAL DOSE OF HYDROCODONEMy little brothers friend just died not to long ago from a hydrocodone overdose. What my brother said is that he died from only taking 4 extra strength vicodin 7.5/750, is that even possible to die from only 4 extra stengths? we dont really believe that this is all that he took but any information would be great, what is a lethal dose and is this possible? It really scares me because i take norco for my split disc in my back, i never take 4 though it just is hard to believe that only 4 could kill someone especially when they had been taking them consistently. ( categories: Discussion of Prescription and OTC Meds )
Everyone reacts differently
Everyone reacts differently to meds but that does seem a little too low of dose. Was the person allergic to opiates or something because that is the only time i can see this being a lethal dose by itself. When I was taking opiates consistenly to get high it was not uncommon for me to eat 10 or more 7.5mg hydros in a day. The lethal dose in humans
The lethal dose in humans varies greatly, essentially a function of weight, efficiency of metabolism, and tolerance. I am not a Dr. I just play one on TV.
That is horrible man
I dont even know what to say man. That is horrible. The pain man of losing a young one over something so preventable is sad. My sincere sympathy goes out to the fam. Like the guy before me said, it all depends on the person, weight, etc.. which determines a fatal dose. 7.5 x 4 = 30 and 750 x 4 = 3000 so thats basically a 30/3000 dose at once..... Sorry about your friend. Had
Sorry about your friend. Had he ever taken hydrocodone before, maybe he was allergic to it.....that dosage would make someone who is opiate niave sick, but I wouldn't think it would kill....SSSSorry about that. I just lost a good friend 2 weeks ago from OD Ray Remember: Just do it.. EVERY PILL EVERY DAY compared to morphine the
compared to morphine the potency of hydrocodone is 1.5, means hydrocodone is 1.5 times stronger than morphine. bioavailability is higher than this of morphine, AFAIK to a non- tolerant adult person, 1.0 - 2.0 mg per kilogramm bodyweight could be dangerous. maybe benzodiazepines and alcohol were consumed with the hydrocodone? too sad another young human died because of drug abuse.
wow..
that is a shame, im sorry to hear that. how old was the kid? you said it was your little brothers friend, so are you talking like 10, 7, beacuse for someone so young to take 4 of those pills, esp if he had never taken any opiates before, anything is possible. like the others said everybody is different, he could have been allergic... who knows. its just a shame to lose someone so young over 4 stupid pills. sorry for the loss. But just curious how old was this littel kid?
I don't think it matters if you are 100 pounds. What matters is the metabolism. A child's metabolism is not fully developed, aside from the boy still needing to go through puberty which in essence a body's blueprint into adulthood. I don't think this is a conspiracy but just unfortunate negligence on some body's end. God Bless that fam man. Wow, something sounds...
...well, suspicious. I myself am 100 pounds soaking wet, gastro surgeries, problems, etc...plus I have MS & migraine headaches, re-occurent pancreantitus and cancer scares (history, plus just had a lump removed benign, Thank God, but mom wasn't so lucky, she was 47 when passing, and I'm 45) Plus, I take a LOT of pain medication and benzodiazipams (xanax, valium, etc.) ANYWAY, I would say no matter WHAT your condition, 4 of any pill-formed narcotic will NOT kill you. And if there were some rare, un-heard-of thing that the Vic. would react that way to, the doc should have seen it coming a mile away. If that turns out to be the case, with a smart atty., the family of this boy can get this docs house, pension-well, everything. Whoever's signature was on that Vicodin r/x has gotta be a little nervous right now. And the parents shoud look into it, THE SOONER THE BETTER! You can't change the outcome, but you can get what you deserve. God Bless...Zelda. Ciao, bella,...
Zelda Saying that any pill formed
Saying that any pill formed narcotic will not cause an overdose at 4 pills is completely rediculous. Give 4 80mg oxycontins to an opiate naive person and it is an almost guaranteed overdose. i would go as far as saying 4 of any schedule three narcotic med should not cause an overdose but schedule II containing oxycontin and morphine meds such as ms contin which come in high doses can deffinitely lead to overdose with 4 pills or less. Also I highly doubt that this kid had them prescribed to him by a doctor I was gonna say that 4 pills
I was gonna say that 4 pills of oxycontin 80 or I think they even make a 160mg pill WILL kill someone who is not opiate tolerant...But for someone who has been on narcotics along time...terminal cancer patients for example....would not bother them. Sorry about you loss, a good friend of mine died of overdose a couple weeks ago..... Ray Remember: Just do it.. EVERY PILL EVERY DAY I am sorry for your loss to
I am sorry for your loss to the OP and Slitter and everyone who has lost. One of my best friends died on april 8th of this year of a heroin and xanax overdose so I know how hard it can be to loose someone you are close to. and the 160mg oxycontin was discontinued a couple years back so they dont make it anymore. I suspect the person was not
I suspect the person was not taking vicoden in the manner prescribed, and it is likely that it was not even prescribed for him. As with many drug overdoses, multiple substances were probably involved including alcohol and benzodiazapines. No matter how smart your attorney is, in the unlikely event that a malpractice award exceeds the doctor's coverage, you would not be able to get his house, or his pension, his practice, or anything else, but a monitary settlement from the doctor's malpractice insurance carrier. Even if you could force the physician into bankrupcy, the practice is usually a separate legal entity, the house is protected form bankrupcy in Florida and Texas, and in my state you can retain a 20% equity in the event of bankrupcy. The house is often in another family member's name to protect it or owned by a LLC. Pensions, Keogh, 401k's are not subject to bankrupcy, I believe, this was clarified in a recent supreme court decision. People do not seem to understand what constitutes malpractice. The doctor must deviate from the accepted standard of care, and this deviation must result in significant harm to the patient. While death would constitute harm, it is unlikely that the doctor prescribed more thant the accepted usual dosage of 1-2 Vicoden every 6 hours. If the doctor prescribed this dosage over a long period of time, and the patient took the maximum dosage and developed liver failure as a result to acetaminophen toxicity, then there might be basis for a suit. ZELDA INCORRECT.
The doctor had no idea that this little boy would take these pills. It was probably prescribed for another person in the household. And lets face it, all these prescription commercials are forcing a problem into our face, which has been going on for 30+ years. I would hate to believe it but these commercials probably have an effect of enticing kids into experimenting with it because it challenges kids to think "oh that wont happen to me" or "mom and dad wont find out" aside from the fact that Drug Free American is sponsored by Alcohol and Tobacco Companies. GOD BLESS THIS FAMILY THOUGH. "...4 of any pill-formed
"...4 of any pill-formed narcotic will NOT kill you...." i think that 4 pills 100 mg of non-timereleased morphine would kill someone who has no opioide / opiate tolerance. I found information that sais 0.4 - 0.5 per kg/bodyweight could be lethal when injected iv, and about 1.0 mg when taken oral. Some people metabolize the
Some people metabolize the codones to the active metabolite very rapidly, so they are at high risk for overdose and toxicity. What are modest doses for most people may be fatal to a rapid metabolizer. There was a news story recently about a woman who was given vicoden for post episiotomy pain. She took a normal dosage as directed, but her breast fed newborn died of narcotic overdose. It turned out that she was an ultra-fast metabolizer. People can be tested for their genetic status for codone metabolism, but it is still generally only a research tool, but it is part of the new field of genetic pharmacology. Why would a woman who is
Why would a woman who is breast feeding their kid be taking vicodin in the first place.......I wonder if she got it from a doc or off the street...>I'm sure that a doctor that has any sense would not prescribe a narcotic to someone who is either pregnant or breast feeding unless it's absolutly necessary. Im sure cases have arisen that require the use of narcotics in pregnant patients, but I would think that it would have to be an extreme case. Ray Remember: Just do it.. EVERY PILL EVERY DAY It is has been, at least
It is has been, at least until recently, standard practice to allow breast feeding women to take narcotic analgesics. When I was a resident, we routinely discharged women on Tylenol #3 for post episiotomy pain, and for pain after c-section or post-partum tubal ligation. The problem of ultra-fast metabolizers has only recently been identified. There may have been other mitigating circumstances in this particular case, such as prematurity, or low birth weight. When I was pregnant with my
When I was pregnant with my 13 yr old, I had migraines and it would cause my blood pressure to rise so I was given Tylenol #3 for the first 5 months of my pregnancy, until the migraines stopped. I remember the doc telling me that "The benefits outweighed the risk" so she went ahead and gave me the Tylenol #3's. Respiratory depression in a
Respiratory depression in a fetus is not particullarly concening since the fetus does not need to breathe. Fetal blood is oxygenated by transfer of oxygen from the maternal circulation to the fetal circulation in the placenta. It is only if the mother stops breathing that the fetus is at risk. Thats Odd. I just read the
Some people metabolize the codones to the active metabolite very rapidly, so they are at high risk for overdose and toxicity. What are modest doses for most people may be fatal to a rapid metabolizer. There was a news story recently about a woman who was given vicoden for post episiotomy pain. She took a normal dosage as directed, but her breast fed newborn died of narcotic overdose. It turned out that she was an ultra-fast metabolizer. People can be tested for their genetic status for codone metabolism, but it is still generally only a research tool, but it is part of the new field of genetic pharmacology.
Thats Odd. I just read the same story, accept it was CODEINE she was taking, and it was found that she had a hyperactive CYP2D6 enzyme, that is responsible for methylmorhine metabolism --> morphine. I will have to find the link.
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Joined: 2008-01-20