What is the general consensus on the best baseline & BT meds?

Posts: 21
Joined: 2008-07-18

Hi all,

I broke my back in the T4 & T5 and my C6, along with several other injuries such as torn ligaments and muscle tissue in a car accident. I was left with a wedge compression fracture and ever since (this was in 2004), I've been in constant pain from dusk to dusk again and again and... you all get the picture. I've been diagnosed with severe chronic pain. 

I first started out on MS Contin with liquid morphine as my baseline and BT meds. I was switched shortly thereafter to methadone with the liquid morphine, but eventually (since at the time I had no tolerance) I couldn't take it anymore, so I was switched to Oxycontin 20mg and Vicodin 5mg 3 times daily (then Vicodin ES-7.5mg-since for BT Vicodin HARDLY compared to liquid morphine). That was my mainstay for quite some time, but eventually my Oxycontin went from 20mg to 40mg. I finally started seeing a pain management specialist. Immediately I had my Oxycontin levels increased to 40mg three times daily and my Vicodin ES and continued with three Vicodin ES daily for BT pain. Well, time went by and eventually I was taking one 80mg of Oxycontin twice daily (it was always the generic kind of Oxycontin because of my insurance; I remained on the Vicodin ES at three a day for a time.); this wasn't cutting the pain enough so I BRIEFLY switched to the generic fentanyl patch–50 micrograms, and that was a disaster: those do NOT last for 72 hrs. At best they help for a day and a 1/2. So I made an emergency visit and it was back to the Oxycontin. Eventually after research, I was switched to generic hydromorphone in the liquid form for my breakthrough pain. That worked well, but it was really cumbersome to tote that big bottle around, so the next month I went onto the 8mg tablets three times daily for BT pain–that worked wonders over Vicodin ES. I stayed on the Oxycontin and my doctor tried to increase it by a small amount; but that meant two scripts daily for it and my insurance wouldn't cover that.

After a while, the Oxycontin suddenly just stopped working all that well. I can't say why, but I've heard that rotation of meds is a good thing to do every so often, maybe a doctor in this forum can confirm or deny that? Anyway, I was given few options, so I chose Kadian. I now take two 100mg capsules daily and one 60mg capsule daily. I also take three 350mg Soma (generic, like most everything) daily. At this moment my back hurts. This is common. Even at this high dosage I'm in pain if I sit too long, mop, do the dishes, vacuum, lug anything around or in any way strain my back. Of course it's nowhere NEAR what it would be if I wasn't medicated, but still, there has to be SOMETHING that works ALL of the time. I do like Kadian most of all scripts I've taken, but at one point I said that too about Oxycontin. When this all first started, the high doses made me loopy and out of it; now that I've acclimated to taking pain meds 'round the clock, I don't feel side effects really, just pain relief. My pain is so bad that I HAVE to take high doses to make the pain go away.

So what I'd like to know is what to do about this? What are ALL of the options for baseline pain relief; I know of Opana, Oxycontin, the various forms of morphine such as my Kadian, Duragesic/fentanyl, and methadone. I don't know of any others. What are the options, and how do all of these compare: I know there are threads about all of these, but I'm looking for a general consenus on what works best for most people. I want to know if I should stick with Kadian or try Opana, or maybe go back to something I tried before.

Likewise, I'd like to know what BT pain meds work best. I know of: Levorphanol (Levo Dromoran), Demerol & Demergan, Percocet/Percodin, Opana IR, Dilaudid (like I take now, and, the liquid I took before), then of course the weak, weak Darvocet/Darvon, codeine, and butorphanol (the last I've never heard of before).

I think, I don't know, but I think that between all of these listed, that's all that is manufactured. So I was going to see about switching to Opana and either Demerol or levorphanol, but I don't know...perhaps I have about the best combo available to me now? All I know is that not all of my pain goes away, and it's a major bother to live with severe back pain. I've considered switching to Oxycontin again, but I don't know what kind of hoops I'd have to jump through to get the dosage right; that's why oxymorphone seems like a decent choice but I don't know. The only meds that have worked for me are: Oxycontin and Kadian for baseline relief and Dilaudid for BT relief. So I welcome any thoughts. At first the 260mg daily of Kadian worked like a charm with the 24mg daily of hydromorphone, but now, not as much. Is there really anything to the notion of med rotations? Has anyone else experienced their baseline med or their BT med not working as well as before, when you first started your regimen? 

Sincerely,

Frustrated & Curious 

 





Posts: 21
Joined: 2008-07-18
Oh yeah...

...and in the BT pain category, also IR morphine liquid and presumably tablets too.



Posts: 594
Joined: 2006-04-12
I would deffinitely look

I would deffinitely look into rotation of baseline meds because obviously you build up your tolerance very quickly and switching between the meds such as kadian, oxycontin, opana would take advantage of incomplete cross tolerance. My choice of baseline med would be the oxycontin and breakthrough with the oxycontin i would choose dilaudid but if i was on a different baseline med than oxycontin like your kadian then I would want roxicodone (immediate release oxycodone). I wouldn't want to take the roxicodone with the oxycontin as I would get the best relief from the two different oxycodone preparations but they are both oxycodone and your tolerance will go up even quicker that way. I prefer the oxycodone then the dilaudid for breakthrough. demerol is rather weak orally (IV is a different story) so for breakthrough meds I would either stick with the dilaudid or look into roxicodone (it comes in 5, 15, 30mg strenghts). Morphine (ms contin, kadian, avinza, etc.) tends to make me too sleepy and lethargic which is why I would prefer the oxycodone for extended release



Posts: 21
Joined: 2008-07-18
I've read that...

...Opana ER is rather potent and that for BT pain, levorphanol is a very efficient and potent drug.

Thank you for your advice, it does seem to be that regular rotations should be implemented into my medical routine.

The pain gets so unbearable that I have to lay down several times daily; it would be nice to feel little to no pain...ugh.

So you'd suggest going back to Oxycontin and sticking with Dilaudid ~or~ to stick with Kadian and switch to roxicodone.

Morphine makes me a little bit sleepy, but not too much, I guess we all have different physiologies. Mine seems to be very adaptive to opioids.




Posts: 21
Joined: 2008-07-18
I'm curious???

Does anyone have any experience with Levo Dromoran?




Posts: 594
Joined: 2006-04-12
I have never seen it or ever

I have never seen it or ever heard of it being prescribed here in the US. 

and the Opana might work good for you but I have no experience with it so my suggestion is Kadian/roxicodone or oxycontin/dilaudid. Opana does come in extended and immediate release forms but as i said I have no experience with it but if you like the kadian the oxymorphone(opana) should work just as good if not better at equipotent doses.  




Posts: 21
Joined: 2008-07-18
Walgreens carries it.

It isn't a common narcotic prescribed, but apparently from research I've done, all of two to four milligrams is enough for four to six hours of pain relief. So I gather it's a potent medication, hence my curiousity. I have called and found it in stock somewhere, but the stock is on hold for another patient. If it can do what I've read about, it would be godsend. The generic name for it is levorphanol. It's a synthetic drug like Duragesic or Demerol or Darvocet.



Goat's picture
Posts: 701
Joined: 2006-11-21
  goodness

  i gotta say that there will always be pain...there is a big danger from being overmedicated...you feel good...too good...you know what i mean and you start doing further damage..which i have done.

kadian and oxycodone works for me....1987 i broke my back..compression fractures....i was 18...19....motorcycle crash at over 120...i laid that ninja down like 5 times.....i started with pain management in 2001.. 2 operations in 04 on the back  .percocets and only 3 a day until 04 ...i was given a extra perc a day ..4 a day...from 2001 till now...3 arm surgeries.2 on the back....never went over 4 percs daily...its hard to believe your drug history compared to mine.  not saying you are lying, i feel sorry that you have been dosed so high so soon...and now what?  i think you answered that....take it easy..and good luck.

I am not a Dr. I just play one on TV.




Posts: 21
Joined: 2008-07-18
I'm not overdosed, I can explain...

I have extensive damage throughout my back that is all inoperable and the pain is absolutely excrutiating. In fact, so much so that I get no euphoria or any of those kinds of side effects from my medication–likewise, I don't get sleepy, dizzy, feel nausea, etc., I simply benefit from pain reduction. It's strange, living like this: I'm sure you can relate. But my doctors are very competent and this as much as they can do, give me medication to ease the pain. I wish I'd never been in that car accident, I'll tell you as someone who knows the pain of wedge compression fractures, if you have one up as high in your back as me, with the wedge all the way to the spinal cord (a very lucky near miss) and the nerve damage that radiates throughout my back, plus the pressure of the wedged bone on the rest of my spine causing pain throughout, and to add to all that, scarred tissue from torn muscles, ligaments and tendons, you must be able to at least empathize. Our situations are obviously different. I was never given the chance at surgery and never will, so I suffer severe pain day in, day out. It will always be this way; I've grown to accept that (one must). I don't know what procedures you were lucky to have had that have allowed you to get by on four Percocets a day, but my situation really does warrant and require a high baseline and a high breakthrough set of drugs for my pain management. Once again, just from sitting here I'm in pain for having been sitting too long (over 15 minutes). I'll have to go lay down soon. Anyway, you are right, there will always be some pain...but four years is a great deal of time in the timeline of getting my health back on track, I think you got a sore deal and probably should be getting more pain treatment, but I don't know how you feel daily. I envy that you were able to get surgery, I wanted that from the get-go but it was a no-go...sigh. I don't sit around feeling sorry for myself, though. But don't worry, I'm in no danger nor overmedicated. My doctor is a damn fine physician and I'm lucky to have found him. 



Posts: 21
Joined: 2008-07-18
Oh yeah...

...I have even had bouts in the past where I've had my arms go paralyzed, it's that bad, the nerve damage. It's gotten better to the point that they only go numb under certain situations, so that's good. But a lot of my pain is radial nerve pain...similar in many regards to fibromyalgia I would guess.



quahog's picture
Posts: 281
Joined: 2006-02-15
Have you spoken to your pain

Have you spoken to your pain management physician about an intrathecal pain pump?        

If you are not familiar with it is a pump which is impanted into your body usually in your abdomen and it supplies medications through a catheter which is placed in your spine.    You can also google it for more information.

 It is quite invasive but it could allow for much better pain relief with less medication.    

 It is also not without risks but for many they are a life saver.

 

 

 

 

 

 

 

 

 

 




Posts: 21
Joined: 2008-07-18
Thanks for the tip

I have not ever spoken with my doctor about the pump, I would have to think long and hard on that...but it may be that soon enough I'll need to do something different. I forgot to mention, but I also sometimes wear the Lidoderm back patch and the intramuscular introduction of lidocaine into my back helps a little, but still not enough between my four meds I take/use. I will ask about it next visit, thank you for the advice.




gcdylan's picture
Posts: 411
Joined: 2007-05-03
barbary, I also am on 3

barbary, I also am on 3 oxycodone (40 mg) and oxycodone for b/t for myself it was the best pain releiver that I have had. I tried the fentanyld patch but I  had a alergic reaction to it I have a history of  many allergies. I have 2 bulging discs along with a preety bad neck injury and other problems from a head on collision. I now have to switch to Morphine ER if this last drug store runs out of the generic Oxycontin. They did have it around the 13th of this month for it is a new drugstore that just opened. I myself am quite worried that I will not have the correct amount of Morphine, basically I am assuming  my doctor will start on   the least amount possible and I wil probably have to wait month to month until the correct amount works I absolutley hate this. As was mentioned maybe the switch will help me because I only had morphine when hospitalized. My Medicare D plan does not pay for brand names. I wish you the best for if these discs keeping getting worse I probably will have to think about surgury which was talked about briefly until I quickly changed the subject I also do not know if my doc will change the b/t medicine to morphine also,I will find out the middle of August. I have read many posts in here that orally Morphine is about 30 to 50  weaker than oxycodonCool-



Goat's picture
Posts: 701
Joined: 2006-11-21
your problems are very close

your problems are very close to mine...i also could use more surgery but they won't as well....due to Arachnoiditis...many many times over the years i have felt totally undermedicated,,but at 41 i am not on a very high dose of meds...30mg kadian twice daily, 2 percs daily, 3 somas and 1600 mgs gabapentin...i have had tons of RF treatments and injections..they did help a lot..and i feel also caused the Arachnoid problem....thanks for your posts..good reading.Cool

 

 

I am not a Dr. I just play one on TV.




Posts: 21
Joined: 2008-07-18
Whoa...

I'm 32, so a decade younger, and I cannot BELIEVE that you don't have a pain specialist that will treat your pain properly. My doctor and the clinic he practices at have the philosophy that no patient, no person, should be living in undue pain.

Meds can't *totally* alleviate the pain, but they certainly can go a long way to making your life more livable. I used to walk with a cane when I didn't get the right doses of medication, and thankfully like the paralysis of limbs of that's history. Of course, I did physical therapy for a while. I slack on my exercises, but I try and do as much as I can remember to. That helped, and so does light exercise like walks or bike rides. I just feel lucky that I didn't end up quadriplegic...just a few millimeters more and I'd be in a wheelchair. But the flipside is that I have great amounts of radial nerve pain, as mentioned. I wonder sometimes that if I had become quadriplegic if I'd be in constant pain?

I know it's morbid, but sometimes it feels like...well, you know I bet. I am disabled. I am on SSDI and SSI, it's all official. But since people can't see my disabilities, they seem to assume I'm fit for duty for any and all things. Even my family seems to forget that I'm disabled. Do you ever encounter that mentality with people? When you became disabled, did you notice people one-by-one sort of disappearing from your life? Boy, I have.

I often feel very alone with all of this; enough so that I go to a shrink too and have my whole set of drugs from that. I've got stomach problems too, so I have a specialist for THAT too.

My freakin' medicine cabinet is like a pharmacy. Some clonazepam here for anxiety, some hydromorphone, Soma and Kadian there for pain (plus my Lidoderm patches), some Protonix and some Donnatal for my stomach, & some Abilify and Lamictal for mood stabilization. I even have trouble sleeping, believe it or not, so I've got temazepam for that. So automatically, bars and the like are basically out of the question. My liver and such are under enough attack, haha. Ain't them vehicular accidents a peachy thing? Tongue out

Back to Medicare, though (for anyone who's on it), I have a number of those meds filled as brand name. Medicare is tricky like that; that's partly why I mentioned my personal pharmacy. Anyone on Medicare should always call their provider and find out if certain brands are covered. You'd be surprised. 




Posts: 21
Joined: 2008-07-18
Do you know why?

Why would your doctor not take into account that you suffer from severe pain? That seems really cruel.



Posts: 21
Joined: 2008-07-18
It was the weirdest thing...

...just slowly, well, actually come to think of it only within a matter of about five months, oxycodone eventually just quit working as well as it had in the beginning. Maybe now it would work proper again, but my high dosage of Kadian (I'm on Medicare and that's brand name, it's covered depending on who your carrier is; mine is AARP and they're great) is comparable to the two 80mg twice daily of oxycodone. I'm intrigued by oxymorphone in spite of the reviews of it I've read here. I think I will ask my doc his opinion of it. He's a well-informed doc and does the conversions to almost perfect accuracy. I really don't know how I'd handle one of those pumps, though. I like to control my medication, and since that's so invasive and like fentanyl, it controls and regulates itself (unless you have those oral fentanyl pills that dissolve under your tongue, or the lollipop...but I'm certain those are both reserved for cancer patients). I don't know, a few people have said that oxymorphone works well with them; and that doctor that posts here backed it up. I just know that when the clock hits such-and-such time, I always (daily) feel the pain coming back full force; and when I'm doing well with my meds, that doesn't happen so much. I don't find myself clock watching for when I can take my next batch like it's a full-time job [groans and laughs at the same time]. That's also why levorphanol appeals to me, but I have not read one post from anyone save the fellow that posted the chart that even knows what it is besides me. You haven't heard of levorphanol have you? It's also called Levo Dromoran. What are your thoughts on Opana ER?



Posts: 13
Joined: 2008-07-17
bt meds

 there is something u can try actiq suckers  great for bt pain . if u do not have ins. u can not afford them  but i have heard that there is now a generac form. talk to your dr. about this. good luck



Goat's picture
Posts: 701
Joined: 2006-11-21
 I have had all types of

 I have had all types of people giving me a hard time for a long time..I got my Medicare card when i was 23...I take 12 diff pills daily...slightly over 20 pills daily....I have thought about switching drs for a few years...when i feel rough mostly...but i do see where my dr is coming from due to my age..to young to be on way high doses for this chronic pain...he has talked of patches but went with the kadian with the new diagnosis of the arachnoid problem...anyway take it easy...Cool

 

I am not a Dr. I just play one on TV.

 

 

 




Posts: 21
Joined: 2008-07-18
What is that?

What is Arachnoiditis? Is it something I could contract from my situation being as that it's so similar to yours?



Goat's picture
Posts: 701
Joined: 2006-11-21
Arachnoiditis....please read barbary

 here is a link...please take a good read...and yes you could get this...i try to warn people here about injections in and around the spinal cord...all though you can get this from other reasons...I remember a couple times I had shots in the cord...that the dr really had to contort me in crazy ways to place the shots..once he did a shot that really tweaked my left leg...now its showing itself in my left leg  pretty good..

check the link

http://en.wikipedia.org/wiki/Arachnoiditis

 

I am not a Dr. I just play one on TV.

 

 

 




Posts: 21
Joined: 2008-07-18
Those are the fentanyl suckers, right?

I think I've heard of them. So they work well, huh?



Posts: 11
Joined: 2008-05-28
yes, they do come in generic form

 I also have severe back and neck troubles (along with almost every other joint in my body). Hydromorphone does work for bt pain that is moderate to severe and the actiq works for the severe bt pain. You do not need to have cancer for these to be perscribed, but you do have to work your way up to them with trials of other combos as well as building tolerence to other meds first. Yes, they are expensive 120 a month runs between $5,000 & $6,400 w/o insurance. I am not sure how medicare D works, they may be stricter on only covering these for cancer patients, but I don't have a problem with my ins.. They will only cover a quantity of 120 per month though. I wish you luck and never give up, there is a combo out there that will make life more tolerable.



Posts: 21
Joined: 2008-07-18
So then...

...am I right, are they fentanyl? Do they come generic?



Posts: 11
Joined: 2008-05-28
you are right

yes, the suckers are fentanyl and yes they come in generic and yes they work.



Goat's picture
Posts: 701
Joined: 2006-11-21
i replied above barbary please read

http://en.wikipedia.org/wiki/Arachnoiditis

 

I am not a Dr. I just play one on TV.

 

 

 




Posts: 21
Joined: 2008-07-18
Oy...

Yeah, it looks like I'm a prime candidate for contracting this. My doctors have told me that over the years my spine will continue to compress where it's wedged, thus pinching the nerves there further. I guess all I can say is that sucks you've got it, I won't be getting any epidurals again, no implants and I hope to high heavens that I either a) never get it, or b) get it later in life. I'm still so young.