Pharmer.org

I'm showing these other treatment options On the John Hopkins site Unless it just doesn't say Sulfa in these drugs names I'm not sure if it would have Sulfa in it :

• Nitrofurantoin is encouraged for use (see Longer Duration Therapy) given rates of SMX/TMP E. coli resistance >10% in all U.S. Regions examined and as a fluoroquinolone-sparing agent for women with mild to moderate symptoms AND allergy to TMP-SMX or Abx Rx in previous 3 months (except for nitrofurantoin) or live in a locality with prevalence of E. coli E. coli resistance of TMP-SMX >20% in women with uncomplicated UTI
• Trimethoprim-sulfamethoxazole DS (Bactrim/Septra) 1 tab PO bid x 3d (preferred for empiric Rx if localprevalencelocal prevalence of E. coliresistancecoli resistance to TMP-SMX < 10-20%; if > 10-20% use fluoroquinolone) --- Check with local laboratory for resistance at least once every 6 months.
• Trimethoprim 300 mg PO qd x 3d (do not use if resistance to TMP-SMX is > 10-20%). Check with local laboratory for E. coliresistancecoli resistance rates every 6 months.
• TMP-SMX and TMP aloneisarefirstalone are first line Rx because it isthey arecheap and there is a critical need to reserve FQs for use in complicated UTIs. Overuse in acute cystitis may lead to resistance.
• Norfloxacin 400 mg PO bid x 3d for women with severe symptoms AND allergy to TMP-SMX or Abx Rx in the last 3 months (except a FQ), or live in locatlitylocality with E. coli resistance >20% in women with acute uncomplicated UTI.
• Ciprofloxacin 250 mg PO bid x 3d .for women with severe symptoms AND allergy to TMP-SMX or Abx Rx in the last 3 months (except a FQ), or live in locatlitylocality with E. coli coli resistance >20% in women with acute uncomplicated UTI
• Ofloxacin 200 mg PO bid x 3d .for women with severe symptoms AND allergy to TMP-SMX or Abx Rx in the last 3 months (except a FQ), or live in locatlitylocality with E. colicoli resistance >20% in women with acute uncomplicated UTI
• Amoxicillin/clavulanate 500/125 mg PO bid x 3d (higher percentage of organisms resistant to amoxicillin alone . This regimen is inferior tociprofloxacinto ciprofloxacin and if amox/clavulanate used, longer duration therapy is indicated (see Longer Duration Therapy)).
• There is no single dose treatment regimens using fluoroquinolones that are FDA-approved that have equal efficacy to the 3-day regimens in terms of sterilization of urine and recurrence rate. Therefore, single dose regimens are to be avoided.
• TMP-SMX is first line Rx because it is cheap and there is a critical need to reserve FQs for use in complicated UTIs. Overuse in acute cystitis may lead to resistance.
• Resistance patterns of E. coliE. colitocoli to TMP-SMX are highly variable across U.S. and can change quickly in a given location. Clinicians need to monitor resistance patterns in their community.A systematic program to identify trends in antimicrobial resistance needed to insure that every woman does not need a culture but is also assured that empiric therapy will most likely work without a test of cure.
• Nitrofurantoin macrocrystals 50 or 100 mg qid PO x 7 d; Nitrofurantoin monohydrate macrocrystals 100 mg bid PO x 7 d
• Amoxicillin/clavulanate 500/125 mg PO bid x 7d (higher percentage of organisms resistant to amoxicillin alone). This
• Trimethoprim-Sulfamethoxazole DS 1 tab PO bid x 5-7d (preferred for empiric Rx if prevalence of E. coliresistancecoli resistance to TMP-SMX <10-20%; if >20% use fluoroquinolone).
• Trimethoprim 100 mg PO bid x 7d.
• Cephalexin 250 mg PO tid x 7d.
• Norfloxacin 400 mg PO bid x 7d.
• Ciprofloxacin 250 mg PO bid x 7d .
• Amoxicillin 250 mg PO tid x 7d.
• Amoxicillin/clavulanate 500/125 mg PO bid x 7d (higher percentage of organisms resistant to amoxicillin alone).
• Amoxicillin 250 mg PO tid x 7d.
• Cephalexin 250 mg PO tid x 7d