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OpanaI have a few questions for those of you who are prescribed Opana, specifically the IR, but ER experience would be appreciated as well. I am currently prescribed Roxicodone 15's three times daily. I am starting to look forward to subsequent doses throughout the day, and this worries me. I need them for pain, but I dont want to start the cycle of habituation. I was wandering if those of you who have taken the Opana IR experience as much euphoria as with oxycodone (assuming you have taken it), or morphine. Is it similar to the feeling of Dilaudid? I was taking hydromorph regularly in the past, and after a week I didnt have any euphoria with it, but still had pain relief. My current doctor is hesitant to prescribe Dilaudid due to its reputation, but said she would try Opana. The Roxi works really well, but as I said I like it a little too much. Any experience would be greatly appreciated. ( categories: Discussion of Prescription and OTC Meds )
The pain management
The pain management specialist who spoke at the Opana conference I went to felt strongly that Opana caused less euphoria than oxycodone. Many pain management specialists in this area use long acting morphines (especially Kadian and Avinza) because they seem to cause less euphoria. I have two patients on Opana ER who are doing really well. Both of them are young men who work in construction related fields. Solo brought up in another thread the idea that even if you are not an addict (psychologicly dependant), you will still experience at least some euphoria from any of the narcotics if you are taking enough to give you pain relief. This alone, doesn't make you addicted. Looking forward to the pain relief you get after your next dosage doesn't necessarily mean you are addicted either.  Ist hand
I was on Opana for about a month and as far as euphoria goes, its nothing like oxycodone(no euphoria). You feel a bit tired, sort of in a fog. I got really the same reaction with kadian, as it made me tired. When I first started oxycodone I had euphoria for a few weeks but that goes away with time. My problem with Opana was you have to take it on an empty stomach and that was hard to do all the time, and frankly I didnt like being tired. It also made my stomach feel weird somewhat nauseated. I felt is was just not for me. I have settled on oxycodone on the form of oxycontin w/ roxicodone for bt as needed. I get no euphoria from OC but somtimes a little form the roxi. I dont know why somtimes and not others though. I try not to take the roxi unless I'm bad shape- cant walk. --MUDEBONE-- PS I was on the ER though.. One of my Opana ER patients
One of my Opana ER patients was in tonight. He said he felt better on Opana than he had on anything else (Fentanyl, morphine, oxycodone, hydrocodone, hydromorphone). He can sleep in a few hours without going into withdrawal. He feels more clear headed, more his normal self. He said he would recommend it to anyone. We switched him from oxycodone to Opana IR for breakthrough today to go along with Opana ER. I only have one patient left on oxycontin. I may talk to him about switching when he comes in again. The empty stomach thing is a consideration. Thanks for the info. I
Thanks for the info. I understand that all narcotics are going to have al least some euphoria. I was just wandering if Opana really has less, and if it is similar to hydromorph. Morphines and morphinones generally have a low oral bioavailability, especially when compared to codones. In my experiences, morphine and its derivatives have less euphoria than codones (when taken orally). Have you had ay patients comment on the efficacy of the IR oxymorph? Any ideas on its duration of action, as MUDBONE also inquired? Also, with the dose anticipation, I know this is separate from addiction, but I would rather stay away from a med that I am becoming attached to. It is not a habituation or an anticipation of euphoria, but I dont want to find out if it leads to that. Differences in oral
Differences in oral bioavailability are taken into account when dosage recommendations are made and usually refer to what percentage of an oral dosage is absorbed versus excreted in the stool, or absorbed and immediately metabolized to a weaker or inactive metabolite. Oral bioavailability should not affect the degree of euphoria at equi-analgesic dosages. Theoretically, I agree.
Theoretically, I agree. But in my personal experience, I have found that equal doses, of oxycodone IR to morphine IR (15 and 30mg respectively) to be alot more euphoric. (I think the conversion is more like 20mg to 30mg oral morphine, so this is a higher dose of morphine than what is needed to equal 15mg oxycodone). This was also true with hydromorphone. I had relatively no euphoria when prescribed 8mg dilaudid, which is equal to 20-25mg oxycodone. I suppose it all comes down to physiology, but I think it also comes down to the fact that morphine/ones do not have the potential for euphoria that codones do. I agree that some people do
I agree that some people do note a difference in the euphoric effect of equianalgesic dosages. I don't think it is the bioavailability that influences the relative euphoric effects of different narcotics however. What you are saying about codones compared to morphine/morphones seems to fit my observations regarding drug of abuse preferences. I think I only have one patient still on oxycontin, and I am using a lot of dilaudid for breakthrough rather than hydrocodone or oxycodone. Opana Not Euphoric
Hi, this is my first post to this forum. I am not a doctor, but am a long time chronic pain sufferer, finishing up my first month of 10 mg Opana ER. I can certainly say there is NO euphoria, but I can't say I use pain meds for the euphoria. I just want pain relief. I also use 4-6 10 mg norco (10mg hydrocodone/325 acetomen.) daily for breakthrough pain, so I'm thinking the doc might want to adjust my dose or give me some IR Opana when I see him next week. When I started reading these forums I was surprised to see that it is considered to be twice as strong as oxycontin, since I've taken percocet and pure oxycodone with good success. Are we able to post questions to medical professionals via this forum? Just curious, and thanks for your time, Bonnie
 Hello, BinkyWe are not
Hello, Binky We are not medical professionals. Most of what you read concerning pain and treatments, even the addiction threads, are posted by persons in similar situations. If you post a medical question in this forum, you might get a lot of opinions- none of which should be construed as medical advice. What works for me might kill you, and what works for you might be terrible for me as well. We can discuss medical situations, just remember that none of us are doctors. gtrplayer  OPANA IS THE MED I HAVE EVER BEEN PRESCRIBED
In My Own Opinion, opana ER is the worst medication I have ever been prescribed and sis not help my pain in the least.... The drug almost killed me and I would never recommend anyone ever TAKE it or even consider it.... It is not worth the pain it put me through all though I have heard of some people actually thinking it was great, as for me uh no, I really almost died, and the pain clinic I go to everyone I talked to about it told me they had a bad experience. Stephanie  interesting - Opana
Thanks - I will keep that in mind in case the doc tries to switch me from Fentanyl to Opana. (we all know the docs try to "take you down after awhile") I am 100% satisfied with the Fentanyl, so I hope not!
__________________________________ KnightMetal I am not an MD. I know by experience only. Consult YOUR MD 1st! |
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